| Characteristic | Details |
|---|---|
| Generic Name | Benzonatate |
| Dosage Form | Capsule |
| Strength | 100 mg, 200 mg |
| Route of Administration | Oral |
| Pharmacological Class | Antitussive |
| Main Indication | Cough Relief |
| Availability | Prescription Only |
| Visit Tessalon Official Site | |
Pharmacokinetics of Tessalon
Tessalon, or Benzonatate, is an oral antitussive agent primarily targeting cough suppression. The pharmacokinetic profile reveals absorption through the gastrointestinal tract. Onset of action occurs within 15 to 20 minutes. Effects persist for 3 to 8 hours. The systemic distribution lacks extensive data but likely localizes in pulmonary tissues, where it exerts a numbing effect. This minimizes the cough reflex through peripheral action on stretch receptors in the lungs. The metabolic pathway involves hydrolysis, predominantly in the liver. Excretion is renal and fecal, although exact percentages remain undefined. Half-life estimation approximates at 3 to 4 hours. Optimal therapeutic impact aligns with regular dosing schedules.
Correct Use of Tessalon
Proper utilization of Tessalon 100 mg requires adherence to prescribed dosage and regimen. Capsules must be swallowed whole to prevent oropharyngeal anesthesia. Chewing or dissolving poses risks of aspiration and choking. Typically administered thrice daily, doses align with severity and frequency of symptoms. Use in children under 10 years old is contraindicated due to the risk of severe side effects. Staggered intake over a 24-hour period maintains consistent symptom management. Adjustments necessitate clinical evaluation, particularly in hepatic impairment. Avoid concurrent administration with other local anesthetics or alcohol, as synergistic effects may exacerbate sedation.
Indications for Tessalon
Tessalon’s primary indication is the symptomatic relief of cough. It is effective in managing coughs unresponsive to other treatments. Ideal for chronic and acute respiratory conditions without productive elements. Not suitable for treating underlying conditions like pneumonia. Physicians may prescribe as adjunct therapy, complementing antibiotics or bronchodilators. Patients should seek professional advice to determine suitability. Some off-label applications exist, though these should be clinically evaluated. Cough persistence post-treatment may indicate underlying pathology requiring further medical investigation.
Pregnancy and Breastfeeding
Benzonatate’s safety profile during pregnancy remains inadequately studied. Animal studies suggest low teratogenic risk, but human data is lacking. Prescribing during pregnancy demands careful consideration of risk versus benefit. Consultation with obstetricians is essential. For breastfeeding mothers, the potential for excretion in milk and subsequent infant exposure is unclear. Given the paucity of information, breastfeeding mothers should proceed with caution. Informed decisions necessitate physician guidance, focusing on infant safety and maternal health.
Tessalon Signs and Symptoms of Overdose
Overdose symptoms with Tessalon 100 mg manifest rapidly. Key indicators include CNS depression, seizures, and cardiac arrest. Symptoms may emerge within 15-20 minutes of ingestion. Immediate medical attention is critical. Treatment involves airway management and symptomatic care. Fatalities have been reported, particularly in children. Emergency protocols prioritize supportive measures and gastric lavage, if within a feasible timeframe. Long-term neurological effects are possible following severe overdose. For more detailed guidance, refer to resources like NCBI.
Is Non-Prescription Tessalon Available?
Tessalon remains prescription-only in most jurisdictions. Non-prescription availability is not recognized due to potential misuse and adverse effects. Healthcare providers must evaluate patient history and symptomatology before issuing prescriptions. Regulatory frameworks ensure appropriate distribution, minimizing misuse. Some countries may have differing regulations, but caution is advised when seeking non-prescription options. Patients should rely on trusted medical advice for cough management.
Data source:
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